Sexual Health

PT-141 (Bremelanotide) Dosage Calculator

A melanocortin receptor agonist that works through the central nervous system to improve sexual arousal. FDA-approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women.

Also known as: Bremelanotide, Vyleesi

Peptide Reconstitution Calculator

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PT-141 (Bremelanotide) -- A melanocortin receptor agonist that works through the central nervous system to improve sexual arousal. FDA-approved as...Route: Subcutaneous injection | Frequency: As needed (max 1x per 24 hours) | Half-life: ~2-4 hours
Below typical range (1 mg - 2 mg)

Your Results

Concentration
2.5 mg/mL
= 2500 mcg/mL
Volume to Draw
0.10 mL
Syringe Units (U-100 insulin syringe)
10.0 units
100 units = 1 mL on a standard U-100 insulin syringe
Doses Per Vial
20 doses
at 250 mcg per dose from a 5mg vial
U-100 Insulin Syringe
0u
50u
100u
10.0 units
0.10 mL
Summary: Add 2 mL of bacteriostatic water to your 5mg vial. To get a 250 mcg dose, draw 0.10 mL (10.0 units) on a U-100 insulin syringe. This vial will provide 20 doses at this dosage.
For research purposes only. This calculator is a mathematical tool and does not constitute medical advice. Always consult with a qualified healthcare professional before using any peptide.

PT-141 (Bremelanotide) Quick Reference

Typical Dose
1 mg - 2 mg
Frequency
As needed (max 1x per 24 hours)
Route
Subcutaneous injection
Half-Life
~2-4 hours
Common Vials
10 mg
Reconstituted Stability
Up to 30 days refrigerated
Note: Inject 45-60 minutes before desired effect. May cause nausea, flushing, or headache. Do not use more than once in 24 hours or more than 8 times per month. May cause temporary skin darkening.

PT-141 (Bremelanotide) Storage

Lyophilized: 2-8 C. Reconstituted: 2-8 C

Stability after reconstitution: Up to 30 days refrigerated. Always use bacteriostatic water for multi-use reconstitution. Label the vial with the reconstitution date and discard after the stability period.

PT-141 (Bremelanotide) Frequently Asked Questions

1-2 mg injected subcutaneously 45-60 minutes before desired effect. Start with 1 mg to assess tolerance. The FDA-approved Vyleesi uses 1.75 mg per dose.
Add 2 mL bacteriostatic water for 5 mg/mL. For 1 mg, draw 0.2 mL (20 units). For 1.75 mg, draw 0.35 mL (35 units). For 2 mg, draw 0.4 mL (40 units).
At 1 mg per dose: 10 doses. At 1.75 mg per dose: approximately 5 doses. At 2 mg per dose: 5 doses.
Effects typically begin 45-60 minutes after injection and can last 6-12 hours. Some users report effects lasting up to 24 hours.
Yes, PT-141 is related to Melanotan II and can cause mild skin darkening (tanning effect), especially with repeated use. This effect is usually temporary and fades after discontinuation.
Do not use more than once in 24 hours. The FDA recommends no more than 8 doses per month. Frequent use may lead to tolerance and diminished effects.